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TVIS44007200
Basic Information
VIS ID
TVIS44007200
Fusion event
HTLV-1-SEMA3E integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q21.11
Reference genome
GRCh37/hg19
Start
83027919/83398603 (Hg38)
End
83027919/83398603 (Hg38)
Orient
-
Location type
Intronic
Target gene
SEMA3E
miRNAs that regulate target gene
hsa-mir-615-3p
;
hsa-mir-6878-3p
;
hsa-mir-6741-3p
;
hsa-mir-642a-5p
;
hsa-mir-6830-3p
;
hsa-mir-3124-3p
;
hsa-mir-4778-3p
;
hsa-mir-877-3p
;
hsa-mir-2276-5p
;
hsa-mir-6892-3p
;
hsa-mir-4667-3p
;
hsa-mir-1470
;
hsa-mir-6809-3p
;
hsa-mir-6833-3p
;
hsa-mir-4768-5p
;
hsa-mir-6873-3p
;
hsa-mir-6867-3p
;
hsa-mir-6817-3p
;
hsa-mir-7110-3p
;
hsa-mir-6845-3p
;
hsa-mir-4685-3p
;
hsa-mir-4287
;
hsa-mir-7113-3p
;
hsa-mir-4469
;
hsa-mir-4284
;
hsa-mir-2276-3p
;
hsa-mir-4638-5p
;
hsa-mir-1307-3p
;
hsa-mir-1304-3p
;
hsa-mir-4532
;
hsa-mir-1247-3p
;
hsa-mir-6890-3p
;
hsa-mir-4753-3p
;
hsa-mir-222-5p
;
hsa-mir-1236-3p
;
hsa-mir-6515-3p
;
hsa-mir-122-3p
;
hsa-mir-6722-5p
;
hsa-mir-1288-3p
;
hsa-mir-6499-3p
;
hsa-mir-17-3p
;
hsa-mir-5693
;
hsa-mir-509-5p
;
hsa-mir-509-3-5p
;
hsa-mir-4418
;
hsa-mir-1250-3p
;
hsa-mir-129-5p
;
hsa-mir-153-5p
;
hsa-mir-3672
;
hsa-mir-4294
;
hsa-mir-4743-5p
;
hsa-mir-4754
;
hsa-mir-4760-3p
;
hsa-mir-5696
;
hsa-mir-579-3p
;
hsa-mir-664a-3p
;
hsa-mir-664b-3p
;
hsa-mir-6812-3p
;
hsa-mir-6864-3p
;
hsa-mir-8055
Nearest miRNA
hsa-mir-10525/Upstream/7483334; hsa-mir-10399/Downstream/8805412;
Nearest TSS
ENST00000635602/Upstream/43449;
ENST00000450977/Downstream/63557;
Nearest CpG islands
None/Target,
chr7-CpG: 39/Upstream/235507
,
chr7-CpG: 30/Downstream/350966
Upstream sequence
TGATGACACCGTTAATCATGAACCCACAGTGCTGAGCATATTATTAACATTAACTTCCTAAAATGAATGAATAAAATACAGCCTGTACCAGAGATCAATT
Downstream sequence
TCTAAGAATAAGATAGATGTTTTCTTTTTTAAATCTTTGTTTTAAAAAACAAAAGGATggctgggcatggtggcttacgccagtaataccagcactttgg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL216
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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