Basic Information
VIS ID
TVIS44007218
Fusion event
HTLV-1-LOC107985675 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p22.31
Reference genome
GRCh37/hg19
Start
8315556/8347515 (Hg38)
End
8315556/8347515 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC107985675
Nearest miRNA
hsa-mir-3690-1/Upstream/220454; hsa-let-7f-2/Downstream/2971099;
Nearest TSS
ENST00000429181/Upstream/176248; ENST00000453306/Downstream/117315;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/419948, chrX-CpG: 144/Downstream/383301
Nearby gene
VCX3B(+117315) ;
Upstream sequence
ATGCAATTCTAGTGTAGTATAACAATTCTAGCATAACGTGCTAACTATTTTAACAAGTAGGTATGGAGGAGaggaagcctgtcccgaaactgcaagatgg
Downstream sequence
ttatggttccctgttaaatatcccaaaacacattttttacttcacccttttttccacttaaaaaaatcttgttattatctttttgtgttcccgttaaatc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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