Basic Information
VIS ID
TVIS44007258
Fusion event
HTLV-1-LOC105375341 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
67746477/68281490 (Hg38)
End
67746477/68281490 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7J
Target gene
LOC105375341
Nearest miRNA
hsa-mir-1183/Upstream/1167093; hsa-mir-10399/Downstream/3026182;
Nearest TSS
ENST00000635602/Upstream/190267; ENST00000447158/Downstream/6743;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/978446, chr7-CpG: 226/Downstream/1315898
Nearby gene
LOC102723427(No orient, 248800)
Upstream sequence
gaggtatagagtttgagaccaggggagtttgagaccagcctggccaacatagagaaaccccatctctactaaaaatacaaaaattatctgggtgtggtgg
Downstream sequence
tgcacacctgtaatctcagctacttgggaggctgaggcaggagaatcgcttgaatccaggaggcagaggttgcagtgagctgagattgtgccactgtaca
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate