Basic Information
VIS ID
TVIS44007284
Fusion event
HTLV-1-C3orf67-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p14.2
Reference genome
GRCh37/hg19
Start
58897168/58911442 (Hg38)
End
58897168/58911442 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA3B
Target gene
C3orf67-AS1
Nearest miRNA
hsa-let-7g/Upstream/3058848; hsa-mir-12124/Downstream/1706363;
Nearest TSS
ENST00000440867/Upstream/62216; ENST00000487624/Downstream/134869;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/324266, chr3-CpG: 57/Downstream/138238
Upstream sequence
tgcatacatgaaatatgtactatgtgattccatttatataaatgtaaaagataggtaatattaatctgttagaagtcagtatagaggttatctcttagga
Downstream sequence
gaaggaaggaagtgatgattgggaggagacataagcaggcttgtaggatgcttgtaatgcttgatctgggtggtggttacagaaatgtgttcactttgtg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate