Basic Information
VIS ID
TVIS44007298
Fusion event
HTLV-1-chr5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
71921222/72625395 (Hg38)
End
71921222/72625395 (Hg38)
Orient
+
Location type
ncRNA_intronic
Nearest miRNA
hsa-mir-10397/Upstream/455855; hsa-mir-103a-1/Downstream/253196;
Nearest TSS
ENST00000502646/Upstream/44418; ENST00000515483/Downstream/35274;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/164597, chr5-CpG: 110/Downstream/190935
Upstream sequence
AGATGGCCCCAAGGTCAAGAGCCCCTTCCTCCCAGATGGCTGTCTTGACCATGGTTTCACAGGCAACTTTTGCCTTCAATTCTGCAGAACTGTGCTGGGG
Downstream sequence
GCATGTACTACAGATGGCTTGTTGGCTCCCATTTTTCCCCTGTCCCCTTTATAATTTAGAAAGAGGCTTAGCTCCTTATCTAATACTTGGAATGTGATAC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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