Basic Information
VIS ID
TVIS44007321
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q36.3
Reference genome
GRCh37/hg19
Start
157248066/157455372 (Hg38)
End
157248066/157455372 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA7I
Nearest miRNA
hsa-mir-10399/Upstream/6021733; hsa-mir-153-2/Downstream/118964;
Nearest TSS
ENST00000635602/Upstream/73551; ENST00000444158/Downstream/10859;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/12824, chr7-CpG: 22/Downstream/12872
Nearby gene
LOC101927914(No orient, 10859)
Upstream sequence
tagtgtgaggtaagggttcaattttattttattttttcacaggtggctctccagctgtcccagcaccatttgttgcaagactgccctttccctattgaat
Downstream sequence
ggtcacagcacccttgttggaaatcagttgaccatagatgtgagggtttatttccagactgtcaattctatcccataatgaagaaagtaccacactattt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate