Basic Information
VIS ID
TVIS44007329
Fusion event
HTLV-1-chr10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
23903599/23614670 (Hg38)
End
23903599/23614670 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1265/Upstream/2118029; hsa-mir-107/Downstream/661015;
Nearest TSS
ENST00000439456/Upstream/175212; ENST00000481700/Downstream/80076;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/174076, chr10-CpG: 21/Downstream/78783
Nearby gene
KIAA1217(+80076) ;
Upstream sequence
GGTTGCTGGCATTGTGAAAGTAGCTGGCTTCCCTCATTTGAGCAAACTTTGCAAGGCCTATAAAAGGAAAAGAAATAATCACTTTTACCTACATGAACTT
Downstream sequence
AACATACATTCCTGTAAGGGGAAGCTATTAGCTCCTCCCCTGAAAAAAGCCCCAGGAAGTGTTTGATTCAGACCTCATGAGATGTGAGAACTCTTACTTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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