Basic Information
VIS ID
TVIS44007331
Fusion event
HTLV-1-KIF5B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p11.22
Reference genome
End
32331808/32042880 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-128-3p ; hsa-mir-1-3p ; hsa-mir-215-5p ; hsa-mir-34a-5p ; hsa-mir-192-5p ; hsa-mir-103a-3p ; hsa-mir-30a-5p ; hsa-mir-16-5p ; hsa-mir-186-5p ; hsa-mir-2054 ; hsa-mir-32-3p ; hsa-mir-3190-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-203a-3p ; hsa-mir-6124 ; hsa-mir-142-3p ; hsa-mir-2053 ; hsa-mir-6073 ; hsa-mir-6862-5p ; hsa-mir-4253 ; hsa-mir-3945 ; hsa-mir-7852-3p ; hsa-mir-4255 ; hsa-mir-641 ; hsa-mir-3617-5p ; hsa-mir-7161-5p ; hsa-mir-548u ; hsa-mir-4282 ; hsa-mir-1296-5p ; hsa-mir-4512 ; hsa-mir-7160-3p ; hsa-mir-6895-5p ; hsa-mir-892a ; hsa-mir-3121-3p ; hsa-mir-450a-1-3p ; hsa-mir-7703 ; hsa-mir-3147 ; hsa-mir-5196-5p ; hsa-mir-4425 ; hsa-mir-4747-5p ; hsa-mir-6828-5p ; hsa-mir-922 ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-5684 ; hsa-mir-4325 ; hsa-mir-92a-3p ; hsa-mir-32-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-92b-3p ; hsa-mir-25-3p ; hsa-mir-633 ; hsa-mir-7-5p ; hsa-mir-4496 ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-646 ; hsa-mir-503-5p ; hsa-mir-548g-3p ; hsa-mir-548av-3p ; hsa-mir-5197-3p ; hsa-mir-548s ; hsa-mir-655-3p ; hsa-mir-374c-5p ; hsa-mir-3926 ; hsa-mir-520f-5p ; hsa-mir-6849-3p ; hsa-mir-3675-3p ; hsa-mir-6771-3p ; hsa-mir-1228-3p ; hsa-mir-1273a ; hsa-mir-1273g-3p ; hsa-mir-4432 ; hsa-mir-4486 ; hsa-mir-451b ; hsa-mir-4649-5p ; hsa-mir-4696 ; hsa-mir-4793-3p ; hsa-mir-508-5p ; hsa-mir-6501-3p ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6720-5p ; hsa-mir-6729-5p ; hsa-mir-766-3p ; hsa-mir-939-3p
Nearest miRNA
hsa-mir-1265/Upstream/1674215; hsa-mir-107/Downstream/3036718;
Upstream sequence
TAACAGCACATCACGTTGTAGAAAGTCACTTTGTATCTCCCTGAACTTCAGCCTCCCCAGCAAAATGACTACTTAGGCAAAAGCTCTGAGAATTAGAAGT
Downstream sequence
CATCATATAAAGTTACTATTAACATCtgagagcttacaatgagtcaggttctaaccattttttatatattattgtatttaatcatcacaaaaccccgtgc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate