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TVIS44007331
Basic Information
VIS ID
TVIS44007331
Fusion event
HTLV-1-KIF5B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
32331808/32042880 (Hg38)
End
32331808/32042880 (Hg38)
Orient
-
Location type
Intronic
Target gene
KIF5B
miRNAs that regulate target gene
hsa-mir-128-3p
;
hsa-mir-1-3p
;
hsa-mir-215-5p
;
hsa-mir-34a-5p
;
hsa-mir-192-5p
;
hsa-mir-103a-3p
;
hsa-mir-30a-5p
;
hsa-mir-16-5p
;
hsa-mir-186-5p
;
hsa-mir-2054
;
hsa-mir-32-3p
;
hsa-mir-3190-5p
;
hsa-mir-30c-5p
;
hsa-mir-30d-5p
;
hsa-mir-30b-5p
;
hsa-mir-30e-5p
;
hsa-mir-203a-3p
;
hsa-mir-6124
;
hsa-mir-142-3p
;
hsa-mir-2053
;
hsa-mir-6073
;
hsa-mir-6862-5p
;
hsa-mir-4253
;
hsa-mir-3945
;
hsa-mir-7852-3p
;
hsa-mir-4255
;
hsa-mir-641
;
hsa-mir-3617-5p
;
hsa-mir-7161-5p
;
hsa-mir-548u
;
hsa-mir-4282
;
hsa-mir-1296-5p
;
hsa-mir-4512
;
hsa-mir-7160-3p
;
hsa-mir-6895-5p
;
hsa-mir-892a
;
hsa-mir-3121-3p
;
hsa-mir-450a-1-3p
;
hsa-mir-7703
;
hsa-mir-3147
;
hsa-mir-5196-5p
;
hsa-mir-4425
;
hsa-mir-4747-5p
;
hsa-mir-6828-5p
;
hsa-mir-922
;
hsa-mir-6838-5p
;
hsa-mir-497-5p
;
hsa-mir-424-5p
;
hsa-mir-195-5p
;
hsa-mir-15b-5p
;
hsa-mir-15a-5p
;
hsa-mir-5684
;
hsa-mir-4325
;
hsa-mir-92a-3p
;
hsa-mir-32-5p
;
hsa-mir-363-3p
;
hsa-mir-367-3p
;
hsa-mir-92b-3p
;
hsa-mir-25-3p
;
hsa-mir-633
;
hsa-mir-7-5p
;
hsa-mir-4496
;
hsa-mir-4524b-5p
;
hsa-mir-4524a-5p
;
hsa-mir-646
;
hsa-mir-503-5p
;
hsa-mir-548g-3p
;
hsa-mir-548av-3p
;
hsa-mir-5197-3p
;
hsa-mir-548s
;
hsa-mir-655-3p
;
hsa-mir-374c-5p
;
hsa-mir-3926
;
hsa-mir-520f-5p
;
hsa-mir-6849-3p
;
hsa-mir-3675-3p
;
hsa-mir-6771-3p
;
hsa-mir-1228-3p
;
hsa-mir-1273a
;
hsa-mir-1273g-3p
;
hsa-mir-4432
;
hsa-mir-4486
;
hsa-mir-451b
;
hsa-mir-4649-5p
;
hsa-mir-4696
;
hsa-mir-4793-3p
;
hsa-mir-508-5p
;
hsa-mir-6501-3p
;
hsa-mir-6512-3p
;
hsa-mir-661
;
hsa-mir-6720-5p
;
hsa-mir-6729-5p
;
hsa-mir-766-3p
;
hsa-mir-939-3p
Nearest miRNA
hsa-mir-1265/Upstream/1674215; hsa-mir-107/Downstream/3036718;
Nearest TSS
ENST00000439456/Upstream/21786;
ENST00000628416/Downstream/13551;
Nearest CpG islands
None/Target,
chr10-CpG: 68/Upstream/113416
,
chr10-CpG: 101/Downstream/12742
Upstream sequence
TAACAGCACATCACGTTGTAGAAAGTCACTTTGTATCTCCCTGAACTTCAGCCTCCCCAGCAAAATGACTACTTAGGCAAAAGCTCTGAGAATTAGAAGT
Downstream sequence
CATCATATAAAGTTACTATTAACATCtgagagcttacaatgagtcaggttctaaccattttttatatattattgtatttaatcatcacaaaaccccgtgc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL127
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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