Basic Information
VIS ID
TVIS44007339
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
121716822/121846114 (Hg38)
End
121716822/121846114 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10392/Upstream/2533102; hsa-let-7a-2/Downstream/253643;
Nearest TSS
ENST00000527297/Upstream/217278; ENST00000526777/Downstream/270101;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/393521, chr11-CpG: 113/Downstream/809456
Nearby gene
SORL1(+212351) ;
Upstream sequence
ggtgaaaccctgtctctactaaaaacacaaaaaaattagccggatgtggtggtgtgcacctgtaatcccagctactcaggaggctgaggcaggggaattg
Downstream sequence
cttgaaccagggaggtggaggttgcagtgagctgagattgtgtcactgcactccagcctgggccacagagcgagactccgtctcaaaaaaaaaaaaaaaa
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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