Basic Information
VIS ID
TVIS44007365
Fusion event
HTLV-1-LOC102723342 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q32.33
Reference genome
GRCh37/hg19
Start
105235135/104768798 (Hg38)
End
105235135/104768798 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC102723342
Nearest miRNA
hsa-mir-1185-1/Upstream/91049; hsa-mir-12121/Downstream/96516;
Nearest TSS
ENST00000550708/Upstream/15080; ENST00000557223/Downstream/551;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/15045, chr14-CpG: 24/Downstream/4128
Nearby gene
AKT1(-552) ;
Upstream sequence
GCACCGGCACATTCTGCAGGCTGTTCCGGCTCAGAGCTCGATGTAGTGCTCTGGGGTAACCTGGGCCCCAGCCTGTCCCCTCCCGCCCCCTGCAGCCCCT
Downstream sequence
CCTCCCACCGCCTGCAGCCCCTCCTCCCGCTCTGTCCAGCTTCGAACAGGCCACTCAGGCCTCCCAGCCTTACTTCCACCGTGGCCCAGGCCATGACCTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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