Basic Information
VIS ID
TVIS44007388
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p21
Reference genome
GRCh37/hg19
Start
45526733/45299594 (Hg38)
End
45526733/45299594 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1301/Upstream/9828108; hsa-mir-10b/Downstream/2078081;
Nearest TSS
ENST00000437798/Upstream/131011; ENST00000472021/Downstream/148501;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/128547, chr2-CpG: 19/Downstream/11338
Nearby gene
LINC01121(No orient, 44653)
Upstream sequence
ATAACCAGTTTGTTTCACCAAATGTCACTGGGATAAGCCTTAGCAGCTGTCTCTAAGAGTTCTCTGTAGTGCAGCCTCTGAAGCAATTTTTGAGGGCTCA
Downstream sequence
TCCCTGACTCATTTTTCATTTTACCCAGGCCCTTAGAAGACTGCACAGCGTTAAGTACCCACCTCCTCACCAGTTTGGAAACTCAAAGGCCGTGGCAGCC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate