Basic Information
VIS ID
TVIS44007427
Fusion event
HTLV-1-LINC01600 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p25.2
Reference genome
GRCh37/hg19
Start
2633884/2633650 (Hg38)
End
2633884/2633650 (Hg38)
Orient
+
Location type
ncRNA_exonic
Target gene
LINC01600
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-6720/Upstream/1243239; hsa-mir-10398/Downstream/220381;
Nearest TSS
ENST00000381078/Upstream/181239; ENST00000440848/Downstream/953;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/387731, chr6-CpG: 53/Downstream/488
Upstream sequence
CCCTAAGCCACTGGAACACTCACGGGAGAAAGCTGGACCTGCTTTGAGGCTCACCTCCCTGCATGCACATCCATCCGGCTTCTCTCAAGAAGCAACctgg
Downstream sequence
tgtctgagagccgttgagtcttcatcccagctctggtatttctctcatgtggccacataaccttgaatgtctgaccttcaatttcttcatctgtacagtg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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