Basic Information
VIS ID
TVIS44007440
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q16.3
Reference genome
GRCh37/hg19
Start
104512253/104064378 (Hg38)
End
104512253/104064378 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10398/Upstream/4939682; hsa-mir-1202/Downstream/2719747;
Nearest TSS
ENST00000381078/Upstream/2136235; ENST00000635857/Downstream/667992;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/2661280, chr6-CpG: 79/Downstream/794866
Nearby gene
HACE1(-663715) ;
Nearest cancer related gene
HACE1(TSG, -663715) ;
Upstream sequence
acacacacttgaatgatttcgaaggcttgtgctgtttttattATTTATTATTTTATTCCTTCAGGAAAGTCACTATCATATAATAACAATTAACAATAAC
Downstream sequence
ATTGCTATTCTCAATAACAAGCATtgtgtgacatttttccaatgcttaaatgtgttaactcatctaatcctcacaacaaccctctgataaatgccaaagt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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