VISDB Viral Integration Site DataBase

VIS ID

TVIS44007474

Fusion event

HTLV-1-TMEM245 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr9

Cytoband

q31.3

Reference genome

Start

End

111861698/109099418 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-374b-5p ; hsa-mir-340-5p ; hsa-mir-106b-5p ; hsa-mir-186-5p ; hsa-mir-221-3p ; hsa-mir-21-5p ; hsa-mir-16-5p ; hsa-mir-222-3p ; hsa-mir-183-5p ; hsa-mir-4662a-5p ; hsa-mir-3129-3p ; hsa-mir-5583-5p ; hsa-mir-93-3p ; hsa-mir-3692-5p ; hsa-mir-6507-5p ; hsa-mir-548a-3p ; hsa-mir-548e-3p ; hsa-mir-548f-3p ; hsa-mir-548ar-3p ; hsa-mir-5582-3p ; hsa-mir-548az-3p ; hsa-mir-374a-5p ; hsa-mir-20a-5p ; hsa-mir-526a ; hsa-mir-523-5p ; hsa-mir-522-5p ; hsa-mir-520c-5p ; hsa-mir-519c-5p ; hsa-mir-519b-5p ; hsa-mir-519a-5p ; hsa-mir-518f-5p ; hsa-mir-518e-5p ; hsa-mir-518d-5p ; hsa-mir-520g-5p ; hsa-mir-142-3p ; hsa-mir-4280 ; hsa-mir-562 ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-7844-5p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-27b-5p ; hsa-mir-873-3p ; hsa-mir-376b-3p ; hsa-mir-376a-3p ; hsa-mir-3157-5p ; hsa-mir-95-3p ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-6801-5p ; hsa-mir-676-5p ; hsa-mir-103b ; hsa-mir-4691-3p ; hsa-mir-646 ; hsa-mir-503-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-205-3p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-5089-5p ; hsa-mir-6728-5p ; hsa-mir-769-3p ; hsa-mir-450b-3p ; hsa-mir-6844 ; hsa-mir-6071 ; hsa-mir-593-3p ; hsa-mir-193a-5p ; hsa-mir-5187-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-187-5p ; hsa-mir-661 ; hsa-mir-4693-3p ; hsa-mir-9-5p ; hsa-mir-6728-3p ; hsa-mir-4686 ; hsa-mir-4712-3p ; hsa-mir-6512-5p ; hsa-mir-6793-3p ; hsa-mir-216b-3p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-4298 ; hsa-mir-1302 ; hsa-mir-3189-3p ; hsa-mir-212-5p ; hsa-mir-600 ; hsa-mir-502-5p ; hsa-mir-6798-3p ; hsa-mir-4640-3p ; hsa-mir-361-3p ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-17-5p ; hsa-mir-20b-5p ; hsa-mir-1273f ; hsa-mir-129-5p ; hsa-mir-193b-5p ; hsa-mir-19a-5p ; hsa-mir-19b-1-5p ; hsa-mir-19b-2-5p ; hsa-mir-3170 ; hsa-mir-3665 ; hsa-mir-3674 ; hsa-mir-3680-3p ; hsa-mir-450b-5p ; hsa-mir-4732-5p ; hsa-mir-507 ; hsa-mir-557 ; hsa-mir-6511b-5p ; hsa-mir-6516-5p ; hsa-mir-657 ; hsa-mir-6811-5p ; hsa-mir-6832-5p ; hsa-mir-6855-5p ; hsa-mir-6890-5p

Nearest miRNA

hsa-let-7a-1/Upstream/53120; hsa-mir-12126/Downstream/412057;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/85764, chr9-CpG: 101/Downstream/19784

Upstream sequence

TTCCAATTTGGGCTTGACTGAACCAAACTTGTTCACTCATATCTCATGCTATCCCAAAACAAGTAAGGCAACTATCAGGATTCATCTCTGCAAAGACATT

Downstream sequence

TCTAGTCATTTACAAACAATTACCAATGCCAGGAGGAACAGCACTCAGCTGTACTTGCTGGTACTTCTCAGGCTGGGTATCCAGGCTATTATAGATATAT