Basic Information
VIS ID
TVIS44007508
Fusion event
HTLV-1-LOC107984176 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
26633574/26344645 (Hg38)
End
26633574/26344645 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC107984176
Nearest miRNA
hsa-mir-1265/Upstream/2068864; hsa-mir-107/Downstream/1944613;
Nearest TSS
ENST00000439456/Upstream/126452; ENST00000356785/Downstream/93558;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/126140, chr10-CpG: 53/Downstream/47060
Nearby gene
GAD2(+40083) ;
Upstream sequence
tattctaaaatgaccaaactgatgcccaggagtaaaagaggaaaacttgcttctgccacaaggaggatgggaagagaagagacaggaaaacagaaaaGGG
Downstream sequence
TTGGGGGAAAGGGAGGCCTCCTGGCTAGGGCTACGTGAGGAGTAGAGACAGTGACATGGCCCAGGGTCAGCCCTGTCCTCCCTCTTTGTCCACATTTGTC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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