Basic Information
VIS ID
TVIS44007513
Fusion event
HTLV-1-LINC02442 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q15
Reference genome
GRCh37/hg19
Start
67969738/67575958 (Hg38)
End
67969738/67575958 (Hg38)
Orient
+
Location type
Intronic
Target gene
LINC02442
Nearest miRNA
hsa-let-7i/Upstream/1324801; hsa-mir-1178/Downstream/1697199;
Nearest TSS
ENST00000382841/Upstream/55876; ENST00000537632/Downstream/11348;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/305691, chr12-CpG: 181/Downstream/72428
Nearby gene
LINC02408(+8827) ;
Upstream sequence
GTTTTTCCTATTTTCCTTACATTAAATGAGTCATAACTTACTGAAACTTAGTGGAAAACCTACTGACAAAAGAAGAATATTGACAATATAAAACCACTGG
Downstream sequence
GGAAATGGTGTGAAGCAAGGAGGAGGTCCCTAAGCCTCTTGAACAGGGCTGATAAGAGTGAAATAGGTGCTCTTCAGAGTCAACGGAAACAGTAGGGATG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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