Basic Information
VIS ID
TVIS44007544
Fusion event
HTLV-1-COX7B2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p12
Reference genome
GRCh37/hg19
Start
46779739/46777722 (Hg38)
End
46779739/46777722 (Hg38)
Orient
-
Location type
Intronic
Target gene
COX7B2
Nearest miRNA
hsa-mir-12113/Upstream/6275603; hsa-mir-1243/Downstream/874947;
Nearest TSS
ENST00000502981/Upstream/302492; ENST00000381582/Downstream/99038;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/387167, chr4-CpG: 61/Downstream/215389
Upstream sequence
ttataagaaagaagggaaggtatgtagttatgaaggctggcagcaagtagatAGCTTCAGTTTAAGAAATGCATAGGATTGTCAAAATAAGAACCAAAAG
Downstream sequence
ACTAGGAAAAACAGAGTTATCATggaatagctggacattgcagctggttcagtccttaactagccatgtgacataaggcaaatactaaacttcttcatgc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate