Basic Information
VIS ID
TVIS44007619
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p16.1
Reference genome
GRCh37/hg19
Start
56774372/56547237 (Hg38)
End
56774372/56547237 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1301/Upstream/546442; hsa-mir-10b/Downstream/3840125;
Nearest TSS
ENST00000437798/Upstream/361467; ENST00000463222/Downstream/1360414;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/361833, chr2-CpG: 81/Downstream/1499270
Nearby gene
CCDC85A(+161063) ;
Upstream sequence
TATCATGATTGAACCAGTAAGAGTCTTAACAAACCAAAAATAATAGGCAAGACCAATGTTAACTTAGCTatttattgaataaatctttaagctcttattt
Downstream sequence
aagcaataaaaacaaaatgatgaagcaatggatgaagctgttcccattctccaggagtttgctatctcatcaggaagatagacctgtacacagataactt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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