Basic Information
VIS ID
TVIS44007677
Fusion event
HTLV-1-NIBAN2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q34.11
Reference genome
End
130330198/127567919 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-16-5p ; hsa-mir-484 ; hsa-mir-92a-3p ; hsa-mir-125a-5p ; hsa-mir-762 ; hsa-mir-1227-5p ; hsa-mir-128-2-5p ; hsa-mir-128-1-5p ; hsa-mir-6845-5p ; hsa-mir-6762-5p ; hsa-mir-6878-5p ; hsa-mir-6781-5p ; hsa-mir-5787 ; hsa-mir-4505 ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-4731-5p ; hsa-mir-3179 ; hsa-mir-6770-5p ; hsa-mir-6746-5p ; hsa-mir-3154 ; hsa-mir-1236-5p ; hsa-mir-1321 ; hsa-mir-134-5p ; hsa-mir-149-3p ; hsa-mir-1827 ; hsa-mir-196b-3p ; hsa-mir-2467-3p ; hsa-mir-30a-3p ; hsa-mir-30d-3p ; hsa-mir-30e-3p ; hsa-mir-3118 ; hsa-mir-3136-5p ; hsa-mir-3164 ; hsa-mir-3180-5p ; hsa-mir-3184-5p ; hsa-mir-3199 ; hsa-mir-3202 ; hsa-mir-3612 ; hsa-mir-3689d ; hsa-mir-3942-3p ; hsa-mir-423-5p ; hsa-mir-4257 ; hsa-mir-4419a ; hsa-mir-4439 ; hsa-mir-4443 ; hsa-mir-4457 ; hsa-mir-4475 ; hsa-mir-4476 ; hsa-mir-4510 ; hsa-mir-4513 ; hsa-mir-4515 ; hsa-mir-4534 ; hsa-mir-4688 ; hsa-mir-4717-5p ; hsa-mir-4728-5p ; hsa-mir-4739 ; hsa-mir-4755-3p ; hsa-mir-4756-5p ; hsa-mir-4802-5p ; hsa-mir-5586-3p ; hsa-mir-6085 ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-650 ; hsa-mir-6512-3p ; hsa-mir-6720-5p ; hsa-mir-6761-5p ; hsa-mir-6785-5p ; hsa-mir-6799-5p ; hsa-mir-6813-5p ; hsa-mir-6820-3p ; hsa-mir-6847-5p ; hsa-mir-6849-3p ; hsa-mir-6851-5p ; hsa-mir-6855-3p ; hsa-mir-6857-3p ; hsa-mir-6873-5p ; hsa-mir-6876-5p ; hsa-mir-6883-5p ; hsa-mir-7515 ; hsa-mir-759 ; hsa-mir-7854-3p ; hsa-mir-7855-5p ; hsa-mir-8052 ; hsa-mir-8080 ; hsa-mir-8082 ; hsa-mir-922
Nearest miRNA
hsa-let-7a-1/Upstream/2874121; hsa-mir-12126/Downstream/122768;
Nearest CpG islands
Upstream sequence
gcctcccaacaactcattaataaggaagaaatcactgaccccatttcaaaaaggagaaaaccaaggTGTACAGGACAGATGTCTGGGAAGCAAATGCTGG
Downstream sequence
GATTCCACCCAGGGCAGCTCCACCAGCCAGGAGAGATCGGCCAGAGAGGAGTTTCTCAGGCAGCCGAGATCCTCATCCTATCTCACTGTTCTCCAGAGTC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate