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TVIS44007707
Basic Information
VIS ID
TVIS44007707
Fusion event
HTLV-1-YARS integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p35.1
Reference genome
GRCh37/hg19
Start
33278591/32812990 (Hg38)
End
33278591/32812990 (Hg38)
Orient
+
Location type
Intronic
Target gene
YARS
miRNAs that regulate target gene
hsa-mir-155-5p
;
hsa-mir-877-3p
;
hsa-mir-423-5p
;
hsa-mir-193b-3p
;
hsa-mir-186-5p
;
hsa-mir-6857-5p
;
hsa-mir-4531
;
hsa-mir-943
;
hsa-mir-4439
;
hsa-mir-3136-5p
;
hsa-mir-4450
;
hsa-mir-5703
;
hsa-mir-4516
;
hsa-mir-4434
;
hsa-mir-4708-5p
;
hsa-mir-6088
;
hsa-mir-4770
;
hsa-mir-143-3p
;
hsa-mir-6857-3p
;
hsa-mir-6855-3p
;
hsa-mir-4513
;
hsa-mir-4645-3p
;
hsa-mir-5585-5p
;
hsa-mir-6514-5p
;
hsa-mir-4802-5p
;
hsa-mir-532-5p
;
hsa-mir-425-5p
;
hsa-mir-6736-5p
;
hsa-mir-4701-3p
;
hsa-mir-1262
;
hsa-mir-1200
;
hsa-mir-432-3p
;
hsa-mir-555
;
hsa-mir-1193
;
hsa-mir-6081
;
hsa-mir-7162-5p
;
hsa-mir-516b-3p
;
hsa-mir-516a-3p
;
hsa-mir-2115-5p
;
hsa-mir-4771
;
hsa-mir-8082
;
hsa-mir-3134
;
hsa-mir-4534
;
hsa-mir-4468
;
hsa-mir-1273f
;
hsa-mir-6761-5p
;
hsa-mir-6774-3p
;
hsa-mir-544b
;
hsa-mir-4324
;
hsa-mir-4506
;
hsa-mir-522-3p
;
hsa-mir-224-3p
;
hsa-mir-4694-3p
;
hsa-mir-194-3p
;
hsa-mir-3154
;
hsa-mir-3165
;
hsa-mir-3179
;
hsa-mir-3185
;
hsa-mir-3190-3p
;
hsa-mir-4494
;
hsa-mir-4499
;
hsa-mir-4524a-3p
;
hsa-mir-4709-3p
;
hsa-mir-5693
;
hsa-mir-6077
;
hsa-mir-6745
;
hsa-mir-6795-5p
;
hsa-mir-6880-5p
;
hsa-mir-6887-5p
;
hsa-mir-7-5p
;
hsa-mir-8071
;
hsa-mir-1245b-3p
;
hsa-mir-922
Nearest miRNA
hsa-mir-12136/Upstream/725983; hsa-mir-101-1/Downstream/519403;
Nearest TSS
ENST00000473358/Upstream/1343;
ENST00000474103/Downstream/3777;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/58611
,
chr1-CpG: 104/Downstream/4084
Upstream sequence
ctggaaggtggaggttgcagtgagccaatattgcaccattgcactccagcctgggcaacaagaacgacactctgtctccaaaaaaaaaaaaaaaaaaacc
Downstream sequence
ttggcttccacaaccctccttatcttaactcaagctgacttcaattcttcaggcagagtttaactctttcaatcaattgccagtcaggaaatctttgaat
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL94
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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