Basic Information
VIS ID
TVIS44007736
Fusion event
HTLV-1-chr10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
70879515/69119759 (Hg38)
End
70879515/69119759 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA10C
Nearest miRNA
hsa-mir-1265/Upstream/1716349; hsa-mir-107/Downstream/2670988;
Nearest TSS
ENST00000439456/Upstream/31641; ENST00000497564/Downstream/3753;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/130181, chr10-CpG: 82/Downstream/4148
Nearby gene
VPS26A(+4393) ;
Upstream sequence
tgagccaccgcgcccggctaacaccaaagatatttaagggggaaaggtaagtgtttgcaacaaatggtgctggaaccatgtagacacaaataagctctca
Downstream sequence
aatcttaccccatactatttgcaaaatttagtttgagatggatctcattttacattttacacctaaatgtaaaagTCCAAATTCTCAAGtcatcaacaga
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate