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TVIS44007750
Basic Information
VIS ID
TVIS44007750
Fusion event
HTLV-1-RAB5B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
56371748/55977964 (Hg38)
End
56371748/55977964 (Hg38)
Orient
+
Location type
Intronic
Target gene
RAB5B
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-340-5p
;
hsa-mir-130b-3p
;
hsa-mir-96-5p
;
hsa-mir-93-5p
;
hsa-mir-22-3p
;
hsa-mir-19b-3p
;
hsa-mir-760
;
hsa-mir-877-3p
;
hsa-mir-615-3p
;
hsa-mir-23b-3p
;
hsa-mir-183-5p
;
hsa-mir-17-5p
;
hsa-let-7c-5p
;
hsa-mir-19a-3p
;
hsa-mir-20a-5p
;
hsa-mir-106a-5p
;
hsa-mir-130a-3p
;
hsa-mir-106b-5p
;
hsa-mir-301a-3p
;
hsa-mir-20b-5p
;
hsa-mir-519c-3p
;
hsa-mir-526b-3p
;
hsa-mir-519b-3p
;
hsa-mir-519d-3p
;
hsa-mir-519a-3p
;
hsa-mir-509-5p
;
hsa-mir-454-3p
;
hsa-mir-301b-3p
;
hsa-mir-509-3-5p
;
hsa-mir-1205
;
hsa-mir-1909-3p
;
hsa-mir-4295
;
hsa-mir-3666
;
hsa-mir-4418
;
hsa-mir-548av-3p
;
hsa-mir-6722-3p
;
hsa-mir-8076
;
hsa-mir-620
;
hsa-mir-1270
;
hsa-mir-3117-3p
;
hsa-mir-3169
;
hsa-mir-4252
;
hsa-mir-4759
;
hsa-mir-6869-5p
;
hsa-mir-8083
;
hsa-mir-4505
;
hsa-mir-4731-5p
;
hsa-mir-5787
;
hsa-mir-6842-3p
;
hsa-mir-154-5p
;
hsa-mir-4802-5p
;
hsa-mir-7160-5p
;
hsa-mir-374a-5p
;
hsa-mir-3609
;
hsa-mir-548ah-5p
;
hsa-mir-185-3p
;
hsa-mir-3924
;
hsa-mir-4656
;
hsa-mir-3150a-5p
;
hsa-mir-3150b-5p
;
hsa-mir-4476
;
hsa-mir-4536-5p
;
hsa-mir-5197-3p
;
hsa-mir-6134
;
hsa-mir-6873-5p
;
hsa-mir-6876-5p
;
hsa-mir-8065
;
hsa-mir-9500
;
hsa-mir-214-3p
;
hsa-mir-6878-5p
;
hsa-mir-6133
;
hsa-mir-6130
;
hsa-mir-6129
;
hsa-mir-6127
;
hsa-mir-4510
;
hsa-mir-4419a
;
hsa-mir-4693-3p
;
hsa-mir-6760-5p
;
hsa-mir-5586-3p
;
hsa-mir-6856-5p
;
hsa-mir-6758-5p
;
hsa-mir-605-3p
;
hsa-mir-1295b-3p
;
hsa-mir-4747-3p
;
hsa-mir-6511a-5p
;
hsa-mir-1910-3p
;
hsa-mir-3714
;
hsa-mir-4283
;
hsa-mir-4489
;
hsa-mir-4430
;
hsa-mir-3652
;
hsa-mir-6836-5p
;
hsa-mir-6132
;
hsa-mir-4275
;
hsa-mir-181c-3p
;
hsa-mir-4796-3p
;
hsa-mir-1277-5p
;
hsa-mir-190a-3p
;
hsa-mir-5192
;
hsa-mir-4644
;
hsa-mir-4306
;
hsa-mir-185-5p
;
hsa-mir-6514-5p
;
hsa-mir-5011-5p
;
hsa-mir-4683
;
hsa-mir-6800-3p
;
hsa-mir-212-3p
;
hsa-mir-132-3p
;
hsa-mir-4520-2-3p
;
hsa-mir-3152-5p
;
hsa-mir-4774-3p
;
hsa-mir-6514-3p
;
hsa-mir-6894-3p
;
hsa-mir-6749-3p
;
hsa-mir-211-5p
;
hsa-mir-204-5p
;
hsa-mir-4685-3p
;
hsa-mir-4287
;
hsa-mir-483-3p
;
hsa-mir-8080
;
hsa-mir-182-5p
;
hsa-mir-31-5p
;
hsa-mir-4443
;
hsa-mir-4453
;
hsa-mir-4538
;
hsa-mir-5579-3p
;
hsa-mir-571
;
hsa-mir-6507-5p
;
hsa-mir-6515-5p
;
hsa-mir-6809-5p
;
hsa-mir-6826-5p
;
hsa-mir-6894-5p
;
hsa-mir-7154-3p
;
hsa-mir-765
;
hsa-mir-766-5p
;
hsa-mir-1273h-5p
;
hsa-mir-1293
;
hsa-mir-149-3p
;
hsa-mir-30b-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-30c-2-3p
;
hsa-mir-3122
;
hsa-mir-3165
;
hsa-mir-340-3p
;
hsa-mir-363-5p
;
hsa-mir-3650
;
hsa-mir-3689a-3p
;
hsa-mir-3689b-3p
;
hsa-mir-3689c
;
hsa-mir-383-3p
;
hsa-mir-3913-5p
;
hsa-mir-4293
;
hsa-mir-4459
;
hsa-mir-4483
;
hsa-mir-450a-1-3p
;
hsa-mir-4684-5p
;
hsa-mir-4728-5p
;
hsa-mir-4761-5p
;
hsa-mir-548c-3p
;
hsa-mir-5589-5p
;
hsa-mir-609
;
hsa-mir-6513-5p
;
hsa-mir-6745
;
hsa-mir-6748-5p
;
hsa-mir-6756-5p
;
hsa-mir-6766-5p
;
hsa-mir-6769a-5p
;
hsa-mir-6769b-5p
;
hsa-mir-6771-3p
;
hsa-mir-6772-5p
;
hsa-mir-6776-5p
;
hsa-mir-6779-5p
;
hsa-mir-6780a-5p
;
hsa-mir-6785-5p
;
hsa-mir-6788-5p
;
hsa-mir-6799-5p
;
hsa-mir-6827-3p
;
hsa-mir-6849-3p
;
hsa-mir-6883-5p
;
hsa-mir-7977
;
hsa-mir-887-5p
Nearest miRNA
hsa-mir-1244-3/Upstream/1640650; hsa-let-7i/Downstream/1216540;
Nearest TSS
ENST00000382841/Upstream/3863;
ENST00000549034/Downstream/8997;
Nearest CpG islands
None/Target,
chr12-CpG: 104/Upstream/3576
,
chr12-CpG: 26/Downstream/29748
Upstream sequence
AGAGTGTCTCCTGGTTCTGTGGTGTTATGGCTCCTTTTTTTAAACTTGTGTTTCTCAAGTCAGGAATTAATAGATAGTGGCCCAAAGCTTTTGACCGTTC
Downstream sequence
AACATCAACTGAAAATTCAGCGAACTTTGTTTTTAGCTATAGTTGCCTCAGTGTTTGGGTGGGAGGGCCACATATTGGGTGTGATTAGGCCATCTGAGGC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL6
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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