Basic Information
VIS ID
TVIS44007750
Fusion event
HTLV-1-RAB5B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q13.2
Reference genome
End
56371748/55977964 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-340-5p ; hsa-mir-130b-3p ; hsa-mir-96-5p ; hsa-mir-93-5p ; hsa-mir-22-3p ; hsa-mir-19b-3p ; hsa-mir-760 ; hsa-mir-877-3p ; hsa-mir-615-3p ; hsa-mir-23b-3p ; hsa-mir-183-5p ; hsa-mir-17-5p ; hsa-let-7c-5p ; hsa-mir-19a-3p ; hsa-mir-20a-5p ; hsa-mir-106a-5p ; hsa-mir-130a-3p ; hsa-mir-106b-5p ; hsa-mir-301a-3p ; hsa-mir-20b-5p ; hsa-mir-519c-3p ; hsa-mir-526b-3p ; hsa-mir-519b-3p ; hsa-mir-519d-3p ; hsa-mir-519a-3p ; hsa-mir-509-5p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-509-3-5p ; hsa-mir-1205 ; hsa-mir-1909-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-4418 ; hsa-mir-548av-3p ; hsa-mir-6722-3p ; hsa-mir-8076 ; hsa-mir-620 ; hsa-mir-1270 ; hsa-mir-3117-3p ; hsa-mir-3169 ; hsa-mir-4252 ; hsa-mir-4759 ; hsa-mir-6869-5p ; hsa-mir-8083 ; hsa-mir-4505 ; hsa-mir-4731-5p ; hsa-mir-5787 ; hsa-mir-6842-3p ; hsa-mir-154-5p ; hsa-mir-4802-5p ; hsa-mir-7160-5p ; hsa-mir-374a-5p ; hsa-mir-3609 ; hsa-mir-548ah-5p ; hsa-mir-185-3p ; hsa-mir-3924 ; hsa-mir-4656 ; hsa-mir-3150a-5p ; hsa-mir-3150b-5p ; hsa-mir-4476 ; hsa-mir-4536-5p ; hsa-mir-5197-3p ; hsa-mir-6134 ; hsa-mir-6873-5p ; hsa-mir-6876-5p ; hsa-mir-8065 ; hsa-mir-9500 ; hsa-mir-214-3p ; hsa-mir-6878-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-4693-3p ; hsa-mir-6760-5p ; hsa-mir-5586-3p ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-605-3p ; hsa-mir-1295b-3p ; hsa-mir-4747-3p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-3714 ; hsa-mir-4283 ; hsa-mir-4489 ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-6836-5p ; hsa-mir-6132 ; hsa-mir-4275 ; hsa-mir-181c-3p ; hsa-mir-4796-3p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-5192 ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-6514-5p ; hsa-mir-5011-5p ; hsa-mir-4683 ; hsa-mir-6800-3p ; hsa-mir-212-3p ; hsa-mir-132-3p ; hsa-mir-4520-2-3p ; hsa-mir-3152-5p ; hsa-mir-4774-3p ; hsa-mir-6514-3p ; hsa-mir-6894-3p ; hsa-mir-6749-3p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-483-3p ; hsa-mir-8080 ; hsa-mir-182-5p ; hsa-mir-31-5p ; hsa-mir-4443 ; hsa-mir-4453 ; hsa-mir-4538 ; hsa-mir-5579-3p ; hsa-mir-571 ; hsa-mir-6507-5p ; hsa-mir-6515-5p ; hsa-mir-6809-5p ; hsa-mir-6826-5p ; hsa-mir-6894-5p ; hsa-mir-7154-3p ; hsa-mir-765 ; hsa-mir-766-5p ; hsa-mir-1273h-5p ; hsa-mir-1293 ; hsa-mir-149-3p ; hsa-mir-30b-3p ; hsa-mir-30c-1-3p ; hsa-mir-30c-2-3p ; hsa-mir-3122 ; hsa-mir-3165 ; hsa-mir-340-3p ; hsa-mir-363-5p ; hsa-mir-3650 ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-383-3p ; hsa-mir-3913-5p ; hsa-mir-4293 ; hsa-mir-4459 ; hsa-mir-4483 ; hsa-mir-450a-1-3p ; hsa-mir-4684-5p ; hsa-mir-4728-5p ; hsa-mir-4761-5p ; hsa-mir-548c-3p ; hsa-mir-5589-5p ; hsa-mir-609 ; hsa-mir-6513-5p ; hsa-mir-6745 ; hsa-mir-6748-5p ; hsa-mir-6756-5p ; hsa-mir-6766-5p ; hsa-mir-6769a-5p ; hsa-mir-6769b-5p ; hsa-mir-6771-3p ; hsa-mir-6772-5p ; hsa-mir-6776-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6785-5p ; hsa-mir-6788-5p ; hsa-mir-6799-5p ; hsa-mir-6827-3p ; hsa-mir-6849-3p ; hsa-mir-6883-5p ; hsa-mir-7977 ; hsa-mir-887-5p
Nearest miRNA
hsa-mir-1244-3/Upstream/1640650; hsa-let-7i/Downstream/1216540;
Upstream sequence
AGAGTGTCTCCTGGTTCTGTGGTGTTATGGCTCCTTTTTTTAAACTTGTGTTTCTCAAGTCAGGAATTAATAGATAGTGGCCCAAAGCTTTTGACCGTTC
Downstream sequence
AACATCAACTGAAAATTCAGCGAACTTTGTTTTTAGCTATAGTTGCCTCAGTGTTTGGGTGGGAGGGCCACATATTGGGTGTGATTAGGCCATCTGAGGC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate