Basic Information
VIS ID
TVIS44007788
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p12
Reference genome
GRCh37/hg19
Start
76111008/75883882 (Hg38)
End
76111008/75883882 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1285-2/Upstream/792968; hsa-mir-10b/Downstream/3765412;
Nearest TSS
ENST00000437798/Upstream/164762; ENST00000445178/Downstream/1102083;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/172869, chr2-CpG: 32/Downstream/3109184
Nearby gene
GCFC2(No orient, 172897)
Upstream sequence
aatgtctattctatacctgtctcaccattgtattttgaaagacgatcacttgttgcctgggcttatgggttcacagcagaaagaaatttgcctcacgatg
Downstream sequence
aatcatacctccagtctgacccatatttaatttagatgatatttagatgagatttttgacttagacttgatgctagaatgggctaagacttttagggcta
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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