Basic Information
VIS ID
TVIS44007815
Fusion event
HTLV-1-LOC105374419 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p14
Reference genome
GRCh37/hg19
Start
39646246/39644626 (Hg38)
End
39646246/39644626 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105374419
Nearest miRNA
hsa-mir-12113/Upstream/232652; hsa-mir-1243/Downstream/857414;
Nearest TSS
ENST00000502981/Upstream/5445; ENST00000529314/Downstream/8578;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/5323, chr4-CpG: 82/Downstream/53113
Nearby gene
SMIM14(No orient, 5765)
Upstream sequence
aagacgctgtctcaaaaaaaaaaaaaTGtatatatatatatgtatgtgtgtgtgtgtatatatatacactatatatatatatacattatatatatacata
Downstream sequence
tTTTGCAGATGGATAAATGCTAAAGAAGGCAAGTGAAAATCGGTAATGAGATACATCTTCATTTTATCATGTTTTGGATTttttttgttttggtttggtt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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