Basic Information
VIS ID
TVIS44007816
Fusion event
HTLV-1-chr4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q23
Reference genome
GRCh37/hg19
Start
101000699/100079542 (Hg38)
End
101000699/100079542 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/1082082; hsa-mir-1243/Downstream/1161253;
Nearest TSS
ENST00000502981/Upstream/71471; ENST00000515782/Downstream/110491;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/128705, chr4-CpG: 33/Downstream/110447
Nearby gene
LOC256880(+41837) ;
Upstream sequence
TCTGAGACTGGGAATTTCCACATCAGAGAATGAAAGCAGAGGAAATTACAACTAGAAGAGACAGTTTAGCTCAACTGTACTTTATCTTGAATCTCAGAGA
Downstream sequence
AATTAGACCACAACTCCCCAGCCACCCTAGCTGCCAGGGGATAGCATGCCTACTCTCAGGGTATTTTGGGCTTTTCTTCGTCCTTGTCCCACAAAAAATA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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