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TVIS44007834
Basic Information
VIS ID
TVIS44007834
Fusion event
HTLV-1-IGF2R integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
160465145/160044113 (Hg38)
End
160465145/160044113 (Hg38)
Orient
+
Location type
Intronic
Target gene
IGF2R
miRNAs that regulate target gene
hsa-mir-16-5p
;
hsa-mir-657
;
hsa-mir-155-5p
;
hsa-mir-9-5p
;
hsa-mir-26b-5p
;
hsa-mir-1271-5p
;
hsa-mir-423-3p
;
hsa-mir-128-3p
;
hsa-mir-211-5p
;
hsa-mir-545-5p
;
hsa-mir-412-3p
;
hsa-mir-377-3p
;
hsa-mir-218-5p
;
hsa-mir-96-3p
;
hsa-mir-2681-3p
;
hsa-mir-548m
;
hsa-mir-8485
;
hsa-mir-7977
;
hsa-mir-4284
;
hsa-mir-24-3p
;
hsa-mir-564
;
hsa-mir-6860
;
hsa-mir-612
;
hsa-mir-5189-5p
;
hsa-mir-3187-5p
;
hsa-mir-1285-3p
;
hsa-mir-383-3p
;
hsa-mir-342-3p
;
hsa-mir-6777-3p
;
hsa-mir-6089
;
hsa-mir-561-5p
;
hsa-mir-6715b-3p
;
hsa-mir-4742-3p
;
hsa-mir-6715a-3p
;
hsa-mir-1178-5p
;
hsa-mir-649
;
hsa-mir-106a-3p
;
hsa-mir-1296-5p
;
hsa-mir-6877-5p
;
hsa-mir-4480
;
hsa-mir-5008-5p
;
hsa-mir-3146
;
hsa-mir-454-3p
;
hsa-mir-4295
;
hsa-mir-3666
;
hsa-mir-301b-3p
;
hsa-mir-301a-3p
;
hsa-mir-130b-3p
;
hsa-mir-130a-3p
;
hsa-mir-4512
;
hsa-mir-6895-5p
;
hsa-mir-519c-3p
;
hsa-mir-519b-3p
;
hsa-mir-519a-3p
;
hsa-mir-1247-3p
;
hsa-mir-1827
;
hsa-mir-1910-3p
;
hsa-mir-3612
;
hsa-mir-4537
;
hsa-mir-455-3p
;
hsa-mir-4756-3p
;
hsa-mir-5186
;
hsa-mir-5694
;
hsa-mir-6499-3p
;
hsa-mir-650
;
hsa-mir-6511a-5p
;
hsa-mir-6516-5p
;
hsa-mir-4252
;
hsa-mir-4719
;
hsa-mir-551b-5p
Nearest miRNA
hsa-mir-10398/Upstream/1279360; hsa-mir-1913/Downstream/6465241;
Nearest TSS
ENST00000381078/Upstream/33775;
ENST00000487607/Downstream/29303;
Nearest CpG islands
None/Target,
chr6-CpG: 120/Upstream/37643
,
chr6-CpG: 43/Downstream/46791
Nearest cancer related gene
IGF2R
(TSG, No orient, 0)
Upstream sequence
AAGTGAACTAAGAAGTAAGCGGCCTCCTGCTTGGGTTGCTAAACAGGTTTCGTTAATTTCTGCTTTGGATATGAGACACATTCTCACCCTTTGGCTGTGT
Downstream sequence
GGCTGTGCTTTCAAAAGACTTTGTGTCTTGGGGTAGCTGAAGCCCTGACAGTAGGGGACAATGTCAGTTTACAGTTGGTGCTGATGCATGTTGCAAGCCA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL6
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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