Basic Information
VIS ID
TVIS44007851
Fusion event
HTLV-1-LOC105373133 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p22.2
Reference genome
GRCh37/hg19
Start
13074033/13055914 (Hg38)
End
13074033/13055914 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105373133
Nearest miRNA
hsa-mir-3690-1/Upstream/1737228; hsa-let-7f-2/Downstream/534378;
Nearest TSS
ENST00000429181/Upstream/11232; ENST00000568788/Downstream/37746;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/79434, chrX-CpG: 52/Downstream/322855
Nearby gene
FAM9C(-11116) ;
Upstream sequence
agggaattgtctgAGGTCCTTTAGCTTCCCCTTTGGAAAATTTATCAACACCTGCACAATGGCGAATTGTCTCCAAATAGAGAGTTCAATGCCTCATACC
Downstream sequence
CAAAACAACTCAAAAACAATAAAGAGGAGAAACAAGAACTGATCACCACCCTGAGGTCTCCACTTCTGTTTCTGGAATGATGTTATAATTTATTTCTGAC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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