Basic Information
VIS ID
TVIS44007857
Fusion event
HTLV-1-chrY integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrY
Cytoband
q11.221
Reference genome
GRCh37/hg19
Start
15820669/13708789 (Hg38)
End
15820669/13708789 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12120/Upstream/229523;
Nearest TSS
ENST00000430575/Upstream/5222; ENST00000250823/Downstream/277724;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/4890, chrY-CpG: 128/Downstream/42676
Nearby gene
TMSB4Y(+2767) ;
Upstream sequence
AGTTGTATGTTTGCTATCATTATGGAGATAAATAACAGAAGAGTAAATAGATTTCAAATTACTAAATTATATATATTTTTGGCAGAATCATTGACGTATA
Downstream sequence
CAGTTTCTTAGACTATATCTGTACATTAAAAACTTAACAGCAACTGTATTGTCAATTTGAAATCAATATATCTTCTAGATGAGGCAAAATTTTCTGGTGG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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