Basic Information
VIS ID
TVIS44007895
Fusion event
HTLV-1-LOC102723809 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
64995749/64529031 (Hg38)
End
64995749/64529031 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA14B
Target gene
LOC102723809
Nearest miRNA
hsa-mir-208a/Upstream/433906; hsa-mir-1185-1/Downstream/256595;
Nearest TSS
ENST00000550708/Upstream/23818; ENST00000554883/Downstream/6874;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/23569, chr14-CpG: 205/Downstream/11125
Upstream sequence
AGTACAAAGAAGGGCCTTTTCAGCCTAGAAACACATGTGATAAAGCTCCTATGAGATTGTGCTCCTTGTTCATCTGTCATCTGCTGTGCTGGTAAGGTGG
Downstream sequence
CTAGTAATAGTGGGTACCCAATTAACATGCTGAATAATGTGAAAACGTGAGTGGAAAACAAAACTTTATTTAAATGGTTGATTCAGAATGATGTTTTAGA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate