Basic Information
VIS ID
TVIS44007905
Fusion event
HTLV-1-chr16 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
31520505/31509184 (Hg38)
End
31520505/31509184 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1225/Upstream/615199; hsa-mir-11401/Downstream/2654394;
Nearest TSS
ENST00000527434/Upstream/713; ENST00000564707/Downstream/125;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/565, chr16-CpG: 31/Downstream/20342
Nearby gene
C16orf58(No orient, 765)
Upstream sequence
GGGGGAGTCCAAAGAGGGAGTGTTTCTGTCCTTGGAACTCACCTTTTCTTCTTTCCATTTCTCCTCTTCTCCTTCCCATCTAGTGCAGCATCTTCACTCC
Downstream sequence
GAAGCAGAAATTTGCCAAAAAAGCATCCTCTTTTTATCAGAAAATAAAATATCCTGGTTTCTTAGCCTGGCATTCTTGGATCCCCACAGTTTGATCCCAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate