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Viral Integration Site DataBase
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TVIS44007908
Basic Information
VIS ID
TVIS44007908
Fusion event
HTLV-1-ORC6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
46729519/46695607 (Hg38)
End
46729519/46695607 (Hg38)
Orient
-
Location type
Exonic
Target gene
ORC6
miRNAs that regulate target gene
hsa-mir-193b-3p
;
hsa-mir-484
;
hsa-mir-92a-3p
;
hsa-mir-122-5p
;
hsa-mir-504-3p
;
hsa-mir-4746-3p
;
hsa-mir-4638-5p
;
hsa-mir-1307-3p
;
hsa-mir-6741-3p
;
hsa-mir-4430
;
hsa-mir-3652
;
hsa-mir-3135b
;
hsa-mir-6836-3p
;
hsa-mir-5001-3p
;
hsa-mir-4465
;
hsa-mir-26b-5p
;
hsa-mir-26a-5p
;
hsa-mir-1297
;
hsa-mir-4284
;
hsa-mir-6829-3p
;
hsa-mir-6791-3p
;
hsa-mir-6778-3p
;
hsa-mir-4772-3p
;
hsa-mir-532-3p
;
hsa-mir-1304-3p
;
hsa-mir-662
;
hsa-mir-6890-3p
;
hsa-mir-548s
;
hsa-mir-6864-3p
;
hsa-mir-3672
;
hsa-mir-3926
;
hsa-mir-6134
;
hsa-mir-7854-3p
;
hsa-mir-769-5p
;
hsa-mir-4786-5p
;
hsa-mir-3190-5p
;
hsa-mir-7162-3p
;
hsa-mir-6849-3p
;
hsa-mir-1273g-3p
;
hsa-mir-1587
;
hsa-mir-194-3p
;
hsa-mir-3620-5p
;
hsa-mir-4252
;
hsa-mir-4417
;
hsa-mir-4486
;
hsa-mir-4492
;
hsa-mir-4498
;
hsa-mir-4649-5p
;
hsa-mir-4656
;
hsa-mir-4675
;
hsa-mir-4741
;
hsa-mir-4793-3p
;
hsa-mir-5001-5p
;
hsa-mir-508-5p
;
hsa-mir-6499-3p
;
hsa-mir-6512-3p
;
hsa-mir-661
;
hsa-mir-6720-5p
;
hsa-mir-6729-5p
;
hsa-mir-6829-5p
;
hsa-mir-762
;
hsa-mir-766-3p
;
hsa-mir-7703
;
hsa-mir-939-3p
Nearest miRNA
hsa-mir-1225/Upstream/12531934; hsa-mir-11401/Downstream/3597009;
Nearest TSS
ENST00000527434/Upstream/498;
ENST00000562132/Downstream/15380;
Nearest CpG islands
None/Target,
chr16-CpG: 29/Upstream/5412
,
chr16-CpG: 39/Downstream/94312
Upstream sequence
GAGAAGAAAACTGTACAGGTCTTGAGAAAAGCAACTTATGAAATTGTTTTGTAGGATTCTAAAGCTGAAAGTGGATAAAAACAAAATGGTAGCCACATCC
Downstream sequence
GGTGTAAAAAAAGCTATATTTGATCGACTGTGTAAACAACTAGAGAAGATTGGACAGCAGGTCGACAGTAAGTATTCTGTAGTTCAAGAATGCGTCATTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL63
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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