Basic Information
VIS ID
TVIS44007938
Fusion event
HTLV-1-chr20 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.13
Reference genome
GRCh37/hg19
Start
47934189/49317652 (Hg38)
End
47934189/49317652 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-103a-2/Upstream/2150594; hsa-mir-1-1/Downstream/546207;
Nearest TSS
ENST00000382410/Upstream/26764; ENST00000489787/Downstream/55298;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/38990, chr20-CpG: 84/Downstream/650
Nearby gene
ZFAS1(No orient, 28394)
Nearest cancer related gene
ZFAS1(TSG, No orient, 28394)
Upstream sequence
tgttggtcaggctggtctcgaactcctgacctcaggtgatccacccgcctcggcctcccaaagtgctgggattttacagacctgagccatggtgcctggc
Downstream sequence
ctcttttgccaattttttaatgaggtcttttgtcttcttgttattgagttctaaaagttctttatatattttggacagcagttctttatcaggtgtgtct
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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