Basic Information
VIS ID
TVIS44007969
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
21587995/21587764 (Hg38)
End
21587995/21587764 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-3691/Upstream/3015884; hsa-mir-10398/Downstream/5559862;
Nearest TSS
ENST00000381078/Upstream/63981; ENST00000244745/Downstream/5004;
Nearest CpG islands
chr6-CpG: 131/Target, None/Upstream, None/Downstream
Nearby gene
SOX4(+5977) ;
Nearest cancer related gene
SOX4(OG, +5977) ;
Upstream sequence
ACCTAGACCGCCTGCTGGGGCCACTGGGGTGGTTTTGCCGCCCCCTCAACCCCTGCCACCCCGGGTCGAGTAGGCAGCTCCACCCGGACGCTTGCGCCAG
Downstream sequence
GGCCTGACTGCCGCGGCTGCCAGCGGAAAGGCAGAGACCAGCTGATCCAAGGAGGACAAAGCGAGCCGAGACCTTCCGCAGAGCTTGGCTTCCTCGTAAC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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