Basic Information
VIS ID
TVIS44007984
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q21.11
Reference genome
GRCh37/hg19
Start
75058206/74145971 (Hg38)
End
75058206/74145971 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/9766714; hsa-mir-10400/Downstream/402572;
Nearest TSS
ENST00000518652/Upstream/42455; ENST00000522339/Downstream/53425;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/169281, chr8-CpG: 52/Downstream/169135
Nearby gene
JPH1(-88733) ;
Upstream sequence
CTTACATGGACTCTGTAGTGAGCAGGGGCAGGAGTGAGTCCAGTGAACAGCCCGAGATACCTACCCTTTGTTCAACTGGCCTGGGGCTGGTGAGGTGGCA
Downstream sequence
GGCTTGCAGACTCGGACAGCAGGCATTCAAATATAAAGACTTAGGAAAAGCAGGTGGGAGTCATGTTTGGAGCAATCCCAGATGGAGTTCCCAGTGGGTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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