VISDB Viral Integration Site DataBase

VIS ID

TVIS44008011

Fusion event

HTLV-1-ARL5B integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr10

Cytoband

p12.31

Reference genome

Start

End

18967064/18678135 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-335-5p ; hsa-mir-186-5p ; hsa-mir-340-5p ; hsa-mir-4257 ; hsa-mir-4464 ; hsa-mir-4748 ; hsa-mir-5010-3p ; hsa-mir-5087 ; hsa-mir-6847-5p ; hsa-mir-181b-3p ; hsa-mir-181b-2-3p ; hsa-mir-34b-5p ; hsa-mir-449c-5p ; hsa-mir-2682-5p ; hsa-mir-3714 ; hsa-mir-3920 ; hsa-mir-4420 ; hsa-mir-4704-3p ; hsa-mir-141-3p ; hsa-mir-200a-3p ; hsa-mir-548f-5p ; hsa-mir-548g-5p ; hsa-mir-548x-5p ; hsa-mir-548aj-5p ; hsa-mir-4728-3p ; hsa-mir-8075 ; hsa-mir-648 ; hsa-mir-3658 ; hsa-mir-4699-5p ; hsa-mir-3591-5p ; hsa-mir-3653-3p ; hsa-mir-30b-3p ; hsa-mir-149-3p ; hsa-mir-512-3p ; hsa-mir-504-3p ; hsa-mir-887-5p ; hsa-mir-1249-5p ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-4419a ; hsa-mir-3689c ; hsa-mir-4510 ; hsa-mir-4728-5p ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6131 ; hsa-mir-6133 ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6785-5p ; hsa-mir-6797-5p ; hsa-mir-6883-5p ; hsa-mir-1273h-5p ; hsa-mir-4425 ; hsa-mir-92a-1-5p ; hsa-mir-299-5p ; hsa-mir-124-3p ; hsa-mir-4517 ; hsa-mir-548an ; hsa-mir-4275 ; hsa-mir-892c-5p ; hsa-mir-1179 ; hsa-mir-590-3p ; hsa-mir-548ay-3p ; hsa-mir-548at-3p ; hsa-mir-548as-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-3134 ; hsa-mir-8082 ; hsa-mir-4534 ; hsa-mir-6884-3p ; hsa-mir-3688-3p ; hsa-mir-7151-5p ; hsa-mir-6074 ; hsa-mir-144-3p ; hsa-mir-1277-5p ; hsa-mir-5581-5p ; hsa-mir-3180-5p ; hsa-mir-548aw ; hsa-mir-376a-2-5p ; hsa-mir-3935 ; hsa-mir-4768-3p ; hsa-mir-665 ; hsa-mir-5680 ; hsa-mir-4330 ; hsa-mir-4668-5p ; hsa-mir-142-3p ; hsa-mir-3152-3p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-513a-5p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-3163 ; hsa-mir-624-3p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-488-3p ; hsa-mir-3191-5p ; hsa-mir-6799-5p ; hsa-mir-7106-5p ; hsa-mir-138-5p ; hsa-mir-133a-5p ; hsa-mir-29b-1-5p ; hsa-mir-6824-3p ; hsa-mir-6764-3p ; hsa-mir-330-5p ; hsa-mir-326 ; hsa-mir-518c-5p ; hsa-mir-5571-5p ; hsa-mir-4536-5p ; hsa-mir-190a-3p ; hsa-mir-5589-3p ; hsa-mir-607 ; hsa-mir-524-5p ; hsa-mir-8063 ; hsa-mir-520d-5p ; hsa-mir-205-3p ; hsa-mir-6768-3p ; hsa-mir-4484 ; hsa-mir-6738-3p ; hsa-mir-544a ; hsa-mir-6828-3p ; hsa-mir-6071

Nearest miRNA

hsa-mir-1265/Upstream/832942; hsa-mir-107/Downstream/1873835;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/18353, chr10-CpG: 23/Downstream/32080

Nearby gene

ARL5B(+124) ;

Upstream sequence

CATCTTTAAACCCATCATTCTTATTGAAGCCCATTTGAGAACTCTTAGAATTAATAGAACCTTTTATAAGGGAATATATGGAATATTTTTTATTGTTAAT

Downstream sequence

GTAACTTAATTCCTTAAAACCTGGAATATTAATATATATAATCTATTAAAAGCTGAAGATTAAATATGTAATTTTTGCTTTTAGTTTCTTGTGTTAGTAT