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TVIS44008018
Basic Information
VIS ID
TVIS44008018
Fusion event
HTLV-1-CCSER2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
86194357/84434601 (Hg38)
End
86194357/84434601 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
CCSER2
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-132-3p
;
hsa-mir-26b-5p
;
hsa-mir-20a-5p
;
hsa-mir-106b-5p
;
hsa-mir-6516-5p
;
hsa-mir-455-3p
;
hsa-mir-6499-3p
;
hsa-mir-298
;
hsa-mir-1827
;
hsa-mir-4537
;
hsa-mir-5186
;
hsa-mir-1247-3p
;
hsa-mir-6511a-5p
;
hsa-mir-1910-3p
;
hsa-mir-495-5p
;
hsa-mir-6864-3p
;
hsa-mir-3672
;
hsa-mir-4633-5p
;
hsa-mir-873-3p
;
hsa-mir-4719
;
hsa-mir-532-5p
;
hsa-mir-3145-5p
;
hsa-mir-1252-3p
;
hsa-mir-3662
;
hsa-mir-548c-3p
;
hsa-mir-32-5p
;
hsa-mir-25-3p
;
hsa-mir-363-3p
;
hsa-mir-367-3p
;
hsa-mir-92a-3p
;
hsa-mir-92b-3p
;
hsa-mir-6867-5p
;
hsa-mir-223-5p
;
hsa-mir-511-3p
;
hsa-mir-522-3p
;
hsa-mir-224-3p
;
hsa-mir-4482-3p
;
hsa-mir-676-5p
;
hsa-mir-138-2-3p
;
hsa-mir-4786-5p
;
hsa-mir-6849-3p
;
hsa-mir-4433a-3p
;
hsa-mir-4459
;
hsa-mir-6500-3p
;
hsa-mir-3614-5p
;
hsa-mir-4761-5p
;
hsa-mir-4293
;
hsa-mir-624-3p
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-519d-3p
;
hsa-mir-93-5p
;
hsa-mir-20b-5p
;
hsa-mir-17-5p
;
hsa-mir-371a-5p
;
hsa-mir-371b-5p
;
hsa-mir-372-5p
;
hsa-mir-373-5p
;
hsa-mir-4698
;
hsa-mir-513c-5p
;
hsa-mir-514b-5p
;
hsa-mir-552-5p
;
hsa-mir-616-5p
;
hsa-mir-8063
;
hsa-mir-149-3p
;
hsa-mir-3160-5p
;
hsa-mir-3175
;
hsa-mir-3606-3p
;
hsa-mir-4267
;
hsa-mir-4662a-3p
;
hsa-mir-4680-5p
;
hsa-mir-4716-3p
;
hsa-mir-4723-5p
;
hsa-mir-4728-5p
;
hsa-mir-508-5p
;
hsa-mir-513a-3p
;
hsa-mir-513c-3p
;
hsa-mir-5698
;
hsa-mir-656-3p
;
hsa-mir-6785-5p
;
hsa-mir-6794-5p
;
hsa-mir-6870-5p
;
hsa-mir-6878-5p
;
hsa-mir-6883-5p
;
hsa-mir-7111-5p
;
hsa-mir-766-3p
Nearest miRNA
hsa-mir-1265/Upstream/8882048; hsa-mir-107/Downstream/1830093;
Nearest TSS
ENST00000439456/Upstream/9419;
ENST00000466105/Downstream/3942;
Nearest CpG islands
None/Target,
chr10-CpG: 68/Upstream/105424
,
chr10-CpG: 49/Downstream/106042
Upstream sequence
ttgtcagatggtttagcaacaaatacatagatgcaaagcaaatgtgtcaatattttaacagttggtaaatataggtgaagggtatattgttgttcattgt
Downstream sequence
agtattcttttgatacttctatttcaagaaatgtttcaagataaaGAGGTTGGAAACTTAATAATATTatagtaagtcatttttatttaatatttactat
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL48
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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