VISDB Viral Integration Site DataBase

VIS ID

TVIS44008032

Fusion event

HTLV-1-ATM integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr11

Cytoband

q22.3

Reference genome

Start

End

108118883/108248156 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-421 ; hsa-mir-101-5p ; hsa-mir-101-3p ; hsa-mir-374a-5p ; hsa-mir-181a-5p ; hsa-mir-100-5p ; hsa-mir-18a-5p ; hsa-mir-19b-3p ; hsa-mir-92a-3p ; hsa-mir-3144-3p ; hsa-mir-181b-5p ; hsa-mir-106a-5p ; hsa-mir-26a-5p ; hsa-mir-223-3p ; hsa-mir-181c-5p ; hsa-mir-203a-3p ; hsa-mir-18b-5p ; hsa-mir-181d-5p ; hsa-mir-4262 ; hsa-mir-4735-3p ; hsa-mir-376c-3p ; hsa-mir-377-3p ; hsa-mir-432-5p ; hsa-mir-218-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-4537 ; hsa-mir-6504-3p ; hsa-mir-4438 ; hsa-mir-7155-3p ; hsa-mir-5007-3p ; hsa-mir-3136-3p ; hsa-mir-186-3p ; hsa-mir-1279 ; hsa-mir-4747-3p ; hsa-mir-543 ; hsa-mir-3133 ; hsa-mir-8070 ; hsa-mir-378a-5p ; hsa-mir-572 ; hsa-mir-4454 ; hsa-mir-6759-3p ; hsa-mir-3653-5p ; hsa-mir-1306-5p ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-30a-5p ; hsa-mir-18a-3p ; hsa-mir-1273e ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-219b-3p ; hsa-mir-2467-3p ; hsa-mir-302f ; hsa-mir-3612 ; hsa-mir-3929 ; hsa-mir-4419b ; hsa-mir-4459 ; hsa-mir-4478 ; hsa-mir-4649-3p ; hsa-mir-4695-5p ; hsa-mir-4722-5p ; hsa-mir-4768-3p ; hsa-mir-485-5p ; hsa-mir-650 ; hsa-mir-6511a-5p ; hsa-mir-665 ; hsa-mir-6746-5p ; hsa-mir-6771-5p ; hsa-mir-6808-5p ; hsa-mir-6840-3p ; hsa-mir-6884-5p ; hsa-mir-6893-5p ; hsa-mir-7160-5p ; hsa-mir-940

Nearest miRNA

hsa-mir-10392/Upstream/4398176; hsa-let-7a-2/Downstream/3099601;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/24914, chr11-CpG: 101/Downstream/249615

Nearest cancer related gene

ATM(TSG, No orient, 0)

Upstream sequence

gtcttttgtgtctggtttctttcactaagcataatgttttcaaagttcatgttttaccatgaatcagtacttcattcatttttattgctgaataatattc

Downstream sequence

agttgtatggatatactccattttacttacccatccatcacctgatggCCTAATGTTTCTTAAATAAAACTCTGTTCCCCAGAGATTTGGTTAACATCCT