Basic Information
VIS ID
TVIS44008054
Fusion event
HTLV-1-chr14 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
69307402/68840685 (Hg38)
End
69307402/68840685 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA14C
Nearest miRNA
hsa-mir-208a/Upstream/1398755; hsa-mir-1185-1/Downstream/3676135;
Nearest TSS
ENST00000550708/Upstream/44432; ENST00000553944/Downstream/38337;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/23797, chr14-CpG: 40/Downstream/34025
Nearby gene
ACTN1(-33438) ;
Upstream sequence
accatggaaacagaaagtagaatgttggtttccagggccaggacatggaggtatggggaattattggttagtgagtatagagtttcagttttacaagata
Downstream sequence
aaaagtgttctagagacagatggtggtgattggttgcacaacattatgaatgcacttaataccactaaactgtgcacttaaaaaatgatgaagatgaggc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate