Basic Information
VIS ID
TVIS44008093
Fusion event
HTLV-1-LOC105374329 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p23.3
Reference genome
GRCh37/hg19
Start
24629366/24406497 (Hg38)
End
24629366/24406497 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105374329
Nearest miRNA
hsa-mir-3125/Upstream/5057992; hsa-mir-10b/Downstream/922143;
Nearest TSS
ENST00000437798/Upstream/45783; ENST00000469850/Downstream/85417;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/45755, chr2-CpG: 148/Downstream/84344
Nearby gene
ITSN2(-45969) ;
Upstream sequence
tgcctaggcctcccaaagggctgagattacaggcgtgagccaccgggccaagccaaagttattaattttaatgtggcttaatttatcattttctttatag
Downstream sequence
ttagtggatttttttttcctacttgagaaGAAAGTTCCTCTGGTCACTCTTTAATAACACAAGTATTTTTTCCTCATTAGTTTAAAAATCCAAATTTAAC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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