Basic Information
VIS ID
TVIS44008103
Fusion event
HTLV-1-LOC105373613 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
130204403/129446830 (Hg38)
End
130204403/129446830 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LOC105373613
Nearest miRNA
hsa-mir-1285-2/Upstream/2023212; hsa-mir-10b/Downstream/2044330;
Nearest TSS
ENST00000437798/Upstream/172982; ENST00000450840/Downstream/430574;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/544457, chr2-CpG: 37/Downstream/140640
Nearby gene
LINC01854(-172939) ;
Upstream sequence
gcacatacacccaCCAAAAATAAACAAGCCACAAGCTCAGGCAGTTTTGGAaggaaattctatattcccaaccaaaataatataaaagagactgtatata
Downstream sequence
tttatctagataaaacaatctgaaaagtagatcaaatatgtaaagccatggtttttaagacactgcaacaaaggacagagattcttgagagagaggaaat
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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