Basic Information
VIS ID
TVIS44008106
Fusion event
HTLV-1-LOC105373786 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
188197730/187333003 (Hg38)
End
188197730/187333003 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105373786
Nearest miRNA
hsa-mir-10b/Upstream/2953959; hsa-mir-1244-1/Downstream/964489;
Nearest TSS
ENST00000437798/Upstream/329729; ENST00000428329/Downstream/115143;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/483661, chr2-CpG: 106/Downstream/958686
Nearby gene
CALCRL(-8960) ;
Upstream sequence
TGCTGTCAGAATGATGTTTACCTTAAAAATAAATGTCCAAACCCAACTGTGTAGATAATAATAATGCTCACATATTTTGTGCTGTACTTGCACCAAGTTT
Downstream sequence
ATATTTAAGCTGATATCTTTTCAGATTTGTTTCTTGAGTTTATGatattattattttaaataattCTCCATGTAACAAACTGATGGGTATTTTAGGACTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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