Basic Information
VIS ID
TVIS44008112
Fusion event
HTLV-1-SYCP2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
58494565/59919510 (Hg38)
End
58494565/59919510 (Hg38)
Orient
-
Location type
Exonic
Target gene
SYCP2
Nearest miRNA
hsa-mir-103a-2/Upstream/1101197; hsa-mir-1-1/Downstream/388964;
Nearest TSS
ENST00000382410/Upstream/3821; ENST00000421092/Downstream/1973;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/313778, chr20-CpG: 184/Downstream/13190
Upstream sequence
GGCTCAGGGCACAGAGAACACAAATTGTTTTTTAAATAAACACATGCTTTATAAATATCAGTGTAATCAATGTGATTTTTACCAGCAGAAGATCAACTAA
Downstream sequence
GTCTTCTATCATATTTAGAACAGCTTCATCTTTTGAATTTCCTTGACTCTGAATAATGTCCTTGGATTTTTCAAACCAGGCAACCATGTAAAAAAAGGAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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