Basic Information
VIS ID
TVIS44008117
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p24.2
Reference genome
GRCh37/hg19
Start
24155476/24113985 (Hg38)
End
24155476/24113985 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA3A
Nearest miRNA
hsa-mir-12127/Upstream/3976344; hsa-let-7g/Downstream/1550888;
Nearest TSS
ENST00000440867/Upstream/10747; ENST00000455576/Downstream/51610;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/167455, chr3-CpG: 135/Downstream/380368
Nearby gene
THRB(-3169) ;
Nearest cancer related gene
THRB(TSG, -3169) ;
Upstream sequence
TCAGGTAACCTTCCTTTATAATGTACttttttttttttttttttttttttttttttttttttttttttttGCATTAGAGTAGGTGAACCTTTTAGGAAGG
Downstream sequence
GAAATGACAAATATTTCCAGAGCAGACTTGCTTTTTTGTTTTTGTAAGGGGCTAAGGCTTTACCCTGGTCTcagtgcaggttgtaaaaagaacatgggtc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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