Basic Information
VIS ID
TVIS44008129
Fusion event
HTLV-1-BST1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p15.32
Reference genome
GRCh37/hg19
Start
15764137/15762514 (Hg38)
End
15764137/15762514 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA4D
Target gene
BST1
Nearest miRNA
hsa-mir-12113/Upstream/2134557; hsa-mir-12115/Downstream/4765761;
Nearest TSS
ENST00000502981/Upstream/47186; ENST00000506191/Downstream/15761;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/59137, chr4-CpG: 72/Downstream/15861
Nearby gene
CD38(+15751) ;
Upstream sequence
ttattacatttaaagttcatttcatttaaaaatatttaattaaaaataaaGATTGAATATATTCAAAGCATACAAGCTTACAACAATCAAATGAACACAT
Downstream sequence
CCATCACCACccatgttgtatattagattctctgaacttataactgaaagtttgtactttttgaccatttcaccatttctgctaaccccaacttcctgac
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate