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TVIS44008141
Basic Information
VIS ID
TVIS44008141
Fusion event
HTLV-1-SLC10A7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q31.22
Reference genome
GRCh37/hg19
Start
147385377/146464225 (Hg38)
End
147385377/146464225 (Hg38)
Orient
-
Location type
Intronic
Target gene
SLC10A7
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-196a-5p
;
hsa-let-7d-5p
;
hsa-mir-484
;
hsa-mir-106b-5p
;
hsa-mir-218-5p
;
hsa-mir-192-3p
;
hsa-mir-4799-5p
;
hsa-mir-5189-3p
;
hsa-mir-6803-5p
;
hsa-mir-6751-5p
;
hsa-mir-7109-5p
;
hsa-mir-4665-5p
;
hsa-mir-1275
;
hsa-mir-3935
;
hsa-mir-6846-5p
;
hsa-mir-6848-5p
;
hsa-mir-4697-5p
;
hsa-mir-4488
;
hsa-mir-1237-5p
;
hsa-mir-6816-5p
;
hsa-mir-3196
;
hsa-mir-3180-3p
;
hsa-mir-3180
;
hsa-mir-6787-5p
;
hsa-mir-663a
;
hsa-mir-1908-5p
;
hsa-mir-4749-5p
;
hsa-mir-4706
;
hsa-mir-4259
;
hsa-mir-6831-5p
;
hsa-mir-3927-3p
;
hsa-mir-577
;
hsa-mir-382-5p
;
hsa-mir-495-5p
;
hsa-let-7c-5p
;
hsa-let-7e-5p
;
hsa-let-7b-5p
;
hsa-let-7a-5p
;
hsa-let-7f-5p
;
hsa-let-7g-5p
;
hsa-mir-4458
;
hsa-mir-4500
;
hsa-let-7i-5p
;
hsa-mir-98-5p
;
hsa-mir-222-3p
;
hsa-mir-221-3p
;
hsa-mir-548v
;
hsa-mir-187-5p
;
hsa-mir-3121-5p
;
hsa-mir-1306-5p
;
hsa-mir-6507-3p
;
hsa-mir-5089-3p
;
hsa-mir-32-5p
;
hsa-mir-92b-3p
;
hsa-mir-92a-3p
;
hsa-mir-181d-5p
;
hsa-mir-181c-5p
;
hsa-mir-181a-5p
;
hsa-mir-181b-5p
;
hsa-mir-132-3p
;
hsa-mir-212-3p
;
hsa-mir-3177-5p
;
hsa-mir-4282
;
hsa-mir-4302
;
hsa-mir-6856-3p
Nearest miRNA
hsa-mir-12113/Upstream/55537; hsa-mir-1305/Downstream/880404;
Nearest TSS
ENST00000502981/Upstream/222419;
ENST00000281321/Downstream/39678;
Nearest CpG islands
None/Target,
chr4-CpG: 46/Upstream/287815
,
chr4-CpG: 84/Downstream/57714
Upstream sequence
cattattttctaatagcaaaaaaaaaagctggaactatcagggctgatattaataattacacatccatacatgagaataataaacagtctataagaagaa
Downstream sequence
tgttgtagaacactatcgagagatgttcacactatattaagtggacaaatagagttacaaaacagtacgcattgtatgactcatttcattaaacatatgt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL48
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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