Basic Information
VIS ID
TVIS44008176
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q36.1
Reference genome
GRCh37/hg19
Start
148241454/148544362 (Hg38)
End
148241454/148544362 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA7I
Nearest miRNA
hsa-mir-10399/Upstream/1166241; hsa-mir-153-2/Downstream/2694059;
Nearest TSS
ENST00000635602/Upstream/40904; ENST00000307003/Downstream/27815;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/204606, chr7-CpG: 200/Downstream/153976
Nearby gene
C7orf33(No orient, 46203)
Upstream sequence
actgatcatgggaccaatttccatagagcgtctcacagaactagtgttttgtggaataaaatttaggaaaATGTGACCCAGCTTCTCCTCCTACACCTAC
Downstream sequence
TTATCCATTTACATGCAAGTCTCCAAATACACTATGTTTCTCCAGGCTGCAATTCCTTGCACATCTGTTCCTTTTCCTGGAATTTCAAGTGGACCATGAG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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