Basic Information
VIS ID
TVIS44008185
Fusion event
HTLV-1-LOC107986971 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.12
Reference genome
GRCh37/hg19
Start
122262654/121250414 (Hg38)
End
122262654/121250414 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA8C ; FRA8E
Target gene
LOC107986971
Nearest miRNA
hsa-mir-12123/Upstream/1925149; hsa-mir-10400/Downstream/1965374;
Nearest TSS
ENST00000518652/Upstream/337349; ENST00000522197/Downstream/388879;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/437934, chr8-CpG: 64/Downstream/389011
Nearby gene
HAS2(-362617) ;
Upstream sequence
TATAGGcagggccagccacataatttgctggccccagtgcaaaatgaaaatgtgtggcccccttattcaaaacgctggaaaaatgccactaaatgtaata
Downstream sequence
aaacatgagcctttttttctttattccatcctttctttctcaacctgtcatggtgttcgttgtttgttatttaatggtgcactcctttgggtgtggggac
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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