VISDB Viral Integration Site DataBase

VIS ID

TVIS44008223

Fusion event

HTLV-1-chr12 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr12

Cytoband

p13.2

Reference genome

Start

End

10442474/10289875 (Hg38)

Orient

-

Location type

Intronic

Target gene

KLRD1 ; LOC105369656

miRNAs that regulate target gene

hsa-mir-1261 ; hsa-mir-4276 ; hsa-mir-151a-3p ; hsa-mir-4641 ; hsa-mir-5190 ; hsa-mir-183-5p ; hsa-mir-5094 ; hsa-mir-4463 ; hsa-mir-4499 ; hsa-mir-1243 ; hsa-mir-365b-3p ; hsa-mir-365a-3p ; hsa-mir-5583-3p ; hsa-mir-186-5p ; hsa-mir-3133 ; hsa-mir-6516-5p ; hsa-mir-5047 ; hsa-mir-1301-3p ; hsa-mir-7156-3p ; hsa-mir-6516-3p ; hsa-mir-1206 ; hsa-mir-3121-5p ; hsa-mir-452-3p ; hsa-mir-501-5p ; hsa-mir-500a-5p ; hsa-mir-651-5p ; hsa-mir-6514-3p ; hsa-mir-6512-3p ; hsa-mir-6720-5p ; hsa-mir-4633-5p ; hsa-mir-4266 ; hsa-mir-6811-3p ; hsa-mir-532-5p ; hsa-mir-4779 ; hsa-mir-4695-5p ; hsa-mir-129-2-3p ; hsa-mir-129-1-3p ; hsa-mir-106a-3p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-5700 ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-6796-3p ; hsa-mir-99b-3p ; hsa-mir-99a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p

Nearest miRNA

hsa-mir-1244-3/Upstream/1050324; hsa-let-7i/Downstream/1822077;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/76409, chr12-CpG: 39/Downstream/323481

Nearby gene

KLRD1(+14576) ;

Upstream sequence

TTGTAAttttttttgtgtgtgtgacagagtttcattcttgttgcccaggctggagtgcagtggtgcagtcttggctcactgcaacctccgcctcccaggt

Downstream sequence

tcaagcgattctcctgcctcagcctcccgagtagctgggattacaggcatgcaccaccacacccagctagttttgtatttttagtagagatggggtttct