Basic Information
VIS ID
TVIS44008226
Fusion event
HTLV-1-SYT1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q21.2
Reference genome
End
79643622/79249842 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-let-7i/Upstream/9665019; hsa-mir-1178/Downstream/169415;
Nearest cancer related gene
SYT1(OG, No orient, 0)
Upstream sequence
CAAGAGAAGGTTAGGTCACCATTCCTGGAGAAATGGAATTTAAAATTTTTCATGTTAACAGCAGTTTAGGAGAATGAAGCCTGTTTTAGAAATTAGAGTA
Downstream sequence
GAATGTAAAGTATCAAAGTTTTGAACCCCAACATCAGAAGTGAATCTCCAAATCAGAATAAGGCAAATTAAGAAAGCTAGAACTCCTTAAAGTCCCCAGA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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