Basic Information
VIS ID
TVIS44008234
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p16.1
Reference genome
GRCh37/hg19
Start
60095626/59868491 (Hg38)
End
60095626/59868491 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1301/Upstream/3867696; hsa-mir-10b/Downstream/518871;
Nearest TSS
ENST00000437798/Upstream/135095; ENST00000444873/Downstream/231709;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1439514, chr2-CpG: 103/Downstream/592196
Nearby gene
MIR4432HG(No orient, 490725)
Upstream sequence
TGATGCTGATGCAGGAAGTAGGGAATAGCATGGGGGACTTTGTGTTTAAGTAACGAAAGAATAGAAGACAGGGTTGGACAGGTACACTGAGTCCTGACCA
Downstream sequence
TAAAGGATTGTAAAGTCAACAGAAAACACAGGACTAAATAGGTCAGCTCATTCAGGAAGGTCTCTAACCACGCATTCAAGAAGGCAAAAGCTGCTCCCAG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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